Screening (of subjects) The process of assessing a large group of potential subjects/patients for enrolment in a trial using a shotgun approach, in which a series of tests-e.g., measurement of cholesterol levels, blood pressure and so on-are used to stratify candidates into yes/no groups before focusing on specific individuals. Screening (of sites) A clinical trial term for assessing the suitability of an investigative site and personnel to participate in a study.
(2) Determining the suitability of an investigative site and personnel to participate in a clinical trial. (1) The evaluation of individuals for potential enrollment in a trial screening (of sites). Get results from both the General dictionary and the Collaborative one through one single interface As we try to make it easy for you to translate into Spanish the English words and expressions, you are given the possibility to see synonyms of a word, conjugate it and obtain the word pronunciation, or even add another meaning to the English-Spanish dictionary. In primary care settings, suicide screening is nearly worthless. (2) An assessment used to identify an increased risk of suicide in a group. (1) Assessment to determine the appropriate services for a client. The use of a low-stringency radiolabelled or biotinylated hybridisation probe to detect gene segments of potential interest from genomic or complementary DNA library. Measured-every 5 years, but not in younger subjects.įaecal-occult blood testing, from age 60 (UK) and age 50 (US). Pap smear every 1-3 years, starting from age of first intercourse.
Measured in normotensive persons every 2 years, all age groups.īreast examination, in women by doctor-every year > age 40 mammography-every 1-2 years, age 35+, every year > age 50. Screening tests have high sensitivities and low specificities, allowing detection of most patients with a morbid condition, while having the acceptable disadvantage of a high rate of false positivity (screening tests by definition have a high sensitivity but low specificity). Screening tests measure specific clinical (e.g., blood pressure for hypertension) or lab parameters (e.g., cholesterol for atherosclerosis or blood in stool for colorectal CA). Screening can be conducted randomly, and substances tested without preselection criteria (which is highly inefficient) or targeted, where information on a substance with known activity and structure is used as a basis for selecting other similar substances on which to run the battery of tests.Ī health service in which all members of a defined and currently asymptomatic population (e.g., sexually active women over age 18 or men over age 50) are evaluated by a screening test to detect a disease process (e.g., cancer (CA) or pre-CA of the uterine cervix in young women, or prostate CA in older men not known to have CA at the time of evaluation). The process by which candidate substances for drug development are evaluated in a battery of assays (screens) designed to detect a specific biological property or activity. The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company.
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